PIVUS-Prospective Investigation of Vasculature in Uppsala Seniors. The PIVUS In March 2006 a reinvesigation of the cohort at the age of 75 was started.

In: Samuel WM, Pybus MJ, Kocan AA, editors. of benzyl benzoate lotion and permethrin in pregnancy: a retrospective matched cohort study.

2014-09-01 · Free Online Library: Persistent organic pollutants and inflammatory markers in a cross-sectional study of elderly Swedish people: the pivus cohort.(Research, Report) by "Environmental Health Perspectives"; Health, general Environmental issues Biological markers Biphenyl (Compound) Analysis C-reactive protein Chlorocarbons Dichloropropane Environmental research Hostages Inflammation Study of Elderly Swedish People: The PIVUS Cohort Jitender Kumar,1 P. Monica Lind,2 Samira Salihovic, 3 Bert van Bavel, Erik Ingelsson,1 and Lars Lind4 1Molecular Epidemiology and Science for Life Laboratory, and 2Occupational and Environmental Medicine, Department of Medical in the male samples from the PIVUS cohort. Homozygote carriers of the G-allele of the SNP rs2179922 were on average 0.90 cm taller than individuals with the two other genotypes at this SNP in the ULSAM cohort and 2.3 cm taller in the PIVUS cohort. No association was observed for the females in the PIVUS cohort. METHODS: The Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) cohort provided plasma samples three times from 2001 to 2014.

7 Dec 2020 The study sample is a subset of the PIVUS cohort. Elderly participants residing in Uppsala, Sweden were eligible and received an invitation to Uppsala Longitudinal Study of Adult Men cohort (R=20.52 for estimated GFR, R= 0.22 for urinary albumin- tion in the ULSAM and PIVUS cohorts. ACR, eGFR extension assay, and plasma leptin in a cohort of middle-aged patients with T2DM. In the replication cohort PIVUS, only A-FABP (p= 0.0003) but not ADM was The PIVUS study started in 2001 with the primary aim to investigate the predicive 16 Jul 2018 (PIVUS) study were examined with MRI of the brain at age 75 years.

We used a total toxic equivalency (TEQ) value that measures toxicological effects with the relative potencies of various POPs.

These individuals were recruited from the Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) cohort. We used a total toxic equivalency (TEQ) value that measures toxicological effects with the relative potencies of various POPs.

Homozygote carriers of the G-allele of the SNP rs2179922 were on average 0.90 cm taller than individuals with the two other genotypes at this SNP in the ULSAM cohort and 2.3 cm taller in the PIVUS cohort. In the PIVUS cohort, GFR was estimated using Gentian reagents (Moss, Norway) according to the formula: estimated GFR = 79.901*cystatin C¯ 1·4389 in PIVUS. Both formulas for the calculation of GFR are closely correlated with plasma iohexol clearance 25 , 26 .

Persistent organic pollutants and inflammatory markers in a cross-sectional study of elderly Swedish people: the pivus cohort.

In the PIVUS study, a cross-sectional analysis revealed that long-chained PFASs, especially PFUnDA, were related to plaque occurrence, but that this association only existed in women. 58 In a longitudinal analysis of the same cohort over 10 years, the change in all of the evaluated PFASs (perfluoroheptanoic acid, PFNA, perfluorodecanoic acid, PFUnDA, PFHxS, PFOS, PFOA, and perfluorooctane The Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS)study is a population-based longitudinal cohort study, started in 2001, of men and women aged 70.

This study has been followed by the PIVUS study, investigat-ing 1000 men and women at ages 70, 75, and 80. Persistent Organic Pollutants and Inflammatory Markers in a Cross-Sectional Study of Elderly Swedish People: The PIVUS Cohort. Jitender Kumar, Circulating FGF-23 is associated with left ventricular hypertrophy (LVH) in a large, community-based cohort (PIVUS study). Our aim was therefore to investigate if intima-media echogenecity is related to cardiovascular risk factors, or to markers of inflammation and oxidation in an exploratory investigation. Methods: The PIVUS cohort study is an observational study of 1016 (509 women and 507 men) randomly chosen individuals aged 70 living in Uppsala, Sweden. It must be acknowledged that PIVUS is an elderly, ethnically homogeneous cohort, limiting the ability to generalize results across other populations. This limitation could be mitigated by the replication of these novel associations between p,p’-DDE and lipid profiles within lipoproteins in epidemiological studies which include a more diverse range of ages and ethnicities.
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cohort, we investigated 504 individuals that contributed with 757 observations of paired BP measurements. The mean baseline systolic and diastolic BPs were 144 (19.7)/76 (9.7) mm Hg, and change in systolic and diastolic BPs were 3.7 (15.8)/−0.5 (8.6) mm Hg over 5 years. BACKGROUND: Persistent organic pollutants (POPs) are compounds that are generated through various industrial activities and released in the surrounding environment. 2008-03-19 · By analyzing the data from the same set of 25 SNPs in the ESR1 gene for association with height in the PIVUS cohort, we observed a clear association signal from the SNP rs2179922 located in intron 4 of ESR1 in males from the PIVUS cohort (p = 0.0056) (Table 2).

As secondary aims, the study also included measurements of cardiac function and structure by ultrasound and MRI, evaluation of atherosclerosis by Assessment of potential confounders of the association between urobilin and sphingomyelin (30:1), and incident heart failure, respectively, in the PIVUS cohort (n = 829, number of events = 58). Table S5. Association of each urobilin metabolite in ULSAM, PIVUS and TwinGene combined – age and sex adjusted.
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Jul 31, 2015 Research Design and Methods: Two community-based cohorts of To our knowledge, PIVUS is the largest cohort with repeated sTNFR1

The longitudinal change in concentration of eight PFASs detected in serum collected from the Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) cohort were determined and compared to results from general population studies. The sex-dependent changes in PFAS concentrations over time were also assessed. Therefore, we conducted this study utilizing measurements of various circulating POPs in a large population-based sample of men and women aged 70 years from the Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) cohort (http://www.medsci.uu.se/pivus/).

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Persistent organic pollutants and inflammatory markers in a cross-sectional study of elderly Swedish people: the PIVUS cohort Environ Health Perspect. 2014 Sep;122(9):977-83. doi: 10.1289/ehp.1307613. Epub 2014 May 23. Authors Jitender

Persistent Organic Pollutants and Inflammatory Markers in a Cross-Sectional Study of Elderly Swedish People: The PIVUS Cohort. Jitender Kumar, time. PIVUS is also a longitudinal population-based study focused on vascular function and body composition (www.medsci.uu.se/ pivus/pivus.htm). The PIVUS cohort consists of 1016 participants with507malesand509femalesofage70bornin1931orlater[13]. Measurements of standing body height were taken at the first sample collectionat age 70. 2016-07-12 2008-03-19 These findings suggest an activation of vascular adhesion molecules by POPs, and particularly by PCB-126. Citation: Kumar J, Lind PM, Salihovic S, van Bavel B, Ingelsson E, Lind L. 2014.

PIVUS - Prospective Investigation of the Vasculature in Uppsala Seniors This study is part of the collection Swedish Cohort Consortium (Cohorts.se), Swedish Diet Cohort Consortium (SDCC) Overview Description Data and documentation Published: 2015-04-19

IMT and the grey scale median (GSM) value were calculated in the intima-media complex Discovery Cohort The PIVUS cohort was used as the discovery cohort.

Human body height is a complex genetic trait with high heritability. We performed an association study of 17 candidate genes for height in the Uppsala Longitudinal Study of Adult Men (ULSAM) that c 2013-12-01 In the PIVUS cohort the PRCP concentrations were significantly correlated ( P < 0.00001) to several symptoms and signs of obesity such as weight, body mass index, abdominal circumference, and waist/hip ratio, and also to blood glucose and markers of lipid metabolism ( Table 1 ). Seniors (PIVUS) cohort.